Visible-Light-Induced FeCl 3 -Promoted Dehydroxypropylative Selenylation of Acyclic Alcohols
Abstract
-promoted dehydroxypropylative selenylation of tertiary acyclic alcohols with diselenides has been developed for constructing unsymmetrical monoselenides. This protocol enables direct C-C bond cleavage and concomitant C-Se bond formation without the need for an additional photocatalyst. The reaction exhibits a broad substrate scope across various diselenides and alcohols and is amenable to gram-scale synthesis. Mechanistic studies support a radical pathway initiated through ligand-to-metal charge transfer (LMCT) upon light irradiation.
Fields of Study & Subjects
Organoselenium and organotellurium chemistry
Sulfur-Based Synthesis Techniques
Radical Photochemical Reactions
Publication details
- Journal / source
- The Journal of Organic Chemistry
- Publisher
- American Chemical Society (ACS)
- Volume
- 91
- Issue
- 18
- Pages
- 6392–6399
- Publication date
- 29 April 2026
- Language
- EN