Thermodynamic Analysis of Protein-Nanoparticle Interactions Links Binding Affinity and Structural Stability

The Journal of Physical Chemistry B 2026

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Authors: Chathuri S. Kariyawasam, Radha P. Somarathne, Naomi C. Hellard, T. H. Shaikh, Nicholas C. Fitzkee
DOI: 10.1021/acs.jpcb.5c07826
Cited by: 1
References: 56

Abstract

< 0.03 for nonfunctionalized PSNPs). These results reveal how protein stability and charge distribution shape adsorption thermodynamics, informing frameworks for predicting protein-surface interactions.

Fields of Study & Subjects

Polymer Surface Interaction Studies Diatoms and Algae Research Nanoparticles: synthesis and applications

Publication details

Journal / source
The Journal of Physical Chemistry B
Publisher
American Chemical Society (ACS)
Volume
130
Issue
5
Pages
1573–1584
Publication date
21 January 2026
Language
EN