Reductive Transformations with Sodium Borohydride and Their Applications
Abstract
Since its discovery by H. C. Brown and H. I. Schlesinger in 1943, sodium borohydride (NaBH 4, SBH) has become one of the most widely used organometallic reducing agents, with applications in the synthesis of pharmaceuticals, agrochemicals, flavors and fragrances, and other industrial sectors like electronics, pulp and paper industry, water treatment and metal recovery, surfactants, textiles, in the hops processing and as a hydrogen carrier. This review focuses on its recent applications in organic synthesis, emphasizing the advantages of SBH over alternative reducing agents and discussing its relevance across key industrial sectors.
Fields of Study & Subjects
Advanced Synthetic Organic Chemistry
Chemical Reactions and Isotopes
Asymmetric Hydrogenation and Catalysis
Publication details
- Journal / source
- Organic Process Research & Development
- Publisher
- American Chemical Society (ACS)
- Volume
- 30
- Issue
- 5
- Pages
- 1082–1118
- Publication date
- 19 March 2026
- Language
- EN