Activation of S–H Bond with Electrophilic Phosphinidenes
Abstract
Phosphinidene complexes have attracted significant interest for their transition metal-like reactivity. We now report that electrophilic phosphinidene complexes, generated in situ from 7-phosphanorbornadiene or 1-thiophosphirane precursors, act as highly effective reagents for direct S–H bond insertion with thiols and thiophenols. This method provides an efficient and straightforward route to diverse P–S-containing scaffolds in good-to-excellent yields. The P–H bond in the products further allows for facile diversification into P–C-coupled derivatives, underscoring the broad utility of this approach.
Fields of Study & Subjects
Synthesis and characterization of novel inorganic/organometallic compounds
Organophosphorus compounds synthesis
Asymmetric Hydrogenation and Catalysis
Publication details
- Journal / source
- Organometallics
- Publisher
- American Chemical Society (ACS)
- Volume
- 45
- Issue
- 3
- Pages
- 241–244
- Publication date
- 23 January 2026
- Language
- EN