Electrochemical Direct C–H Fluorination of Hydrazones
Abstract
In this work, we present a mild and efficient electrochemical method for the direct C–H fluorination of aldehyde hydrazones using KF as an inexpensive and readily available fluorine source. This direct electrochemical approach could tolerate various functional groups, affording a diverse collection of ( Z )-fluorinated hydrazones. Cyclic voltammetry and associated mechanistic investigations were conducted to provide insight into the radical mechanistic pathway.
Fields of Study & Subjects
Fluorine in Organic Chemistry
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Volume
- 28
- Issue
- 7
- Pages
- 2219–2223
- Publication date
- 12 February 2026
- Language
- EN