Photodriven Iron-Catalyzed Selective Oxidative Coupling of Benzylic Alcohols to Afford 1,2-Diols under Air

Organic Letters 2026

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Authors: Tongyu Han, Quansheng Mou, Jinya Li, Shiqian Zhang, Bowen Cao, Chao-Jun Li, Mingxin Liu
DOI: 10.1021/acs.orglett.5c04844
Cited by: 1
References: 32

Abstract

In light of future sustainability and social/environmental well-being, the integration of abundant metal catalysts with cost-effective, readily available oxidants to achieve high-value transformations of chemicals holds significant importance in green chemistry. Herein, we have disclosed an iron-catalyzed selective oxidative coupling of benzylic alcohols into 1,2-diols under air. Particularly in this study, overoxidation to aldehydes or carboxylic acids was efficiently avoided. This offers an efficient and economical route for the selective oxidation of benzyl alcohol.

Fields of Study & Subjects

Oxidative Organic Chemistry Reactions Catalytic C–H Functionalization Methods Asymmetric Hydrogenation and Catalysis

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
2
Pages
710–715
Publication date
2 January 2026
Language
EN