Exploring a Unique Class II Diterpene Cyclase: The Modified Catalytic Acid Motif Contributes to Ring Contraction in Premutilin Synthase

Organic Letters 2026 Open access

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Authors: Kristin Helwig, Jun Xie, Cody Lemke, Meimei Xu, Xinye Kang, Meirong Jia, Reuben J. Peters
DOI: 10.1021/acs.orglett.5c04898
Cited by: 1
References: 15

Abstract

-en-5β-ol-15-PP, providing insight into this unique reaction.

Fields of Study & Subjects

Veterinary medicine and infectious diseases Pharmacological Effects of Natural Compounds Coccidia and coccidiosis research

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
5
Pages
1569–1572
Publication date
21 January 2026
Language
EN