Photocatalytic Access to Cyclopropanes Via Triplet Carbene Transfer from Acceptor-Acceptor Diazoalkanes

Organic Letters 2026

View at publisher
Authors: Mengyu Gao, Chuanyang Song, Xintao Liu, Jingjing Zhao, Pan Li
DOI: 10.1021/acs.orglett.5c04925
Cited by: 10
References: 50

Abstract

A visible-light photocatalytic cyclopropanation of diverse alkenes using acceptor-acceptor diazoalkanes has been developed. The protocol provides an efficient and practical approach to donor-acceptor cyclopropanes under mild conditions. Experimental evidence confirms a mechanism involving a highly electrophilic triplet acceptor-acceptor carbene intermediate, followed by ultrafast intersystem crossing and ring closure.

Fields of Study & Subjects

Cyclopropane Reaction Mechanisms Radical Photochemical Reactions Synthesis and Reactivity of Heterocycles

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
2
Pages
752–757
Publication date
1 January 2026
Language
EN