A Palladium(II)-Catalyzed Dehydrogenative Strategy to NIR-Emissive BODIPY Dimers and Trimers with Reactive Oxygen Species Generation Characteristics

Organic Letters 2026

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Authors: C. Y. Pan, Zhengxin Kang, Fan Lv, Xiankang Zhang, Liang Zhang, Long Wang, Jiangang Gao, Erhong Hao, Lijuan Jiao
DOI: 10.1021/acs.orglett.5c05112
Cited by: 4
References: 53

Abstract

A highly regioselective, one-pot synthesis of directly β,β -linked BODIPY dimers and trimers via a novel palladium-catalyzed oxidative C–H coupling is reported. These oligomers exhibit intense intramolecular J -type exciton coupling, leading to tunable NIR absorption/emission in the 500–800 nm range, decent fluorescence quantum yields, and efficient reactive oxygen species generation, highlighting their potential as dual near-infrared imaging and theranostic agents.

Fields of Study & Subjects

Luminescence and Fluorescent Materials Nanoplatforms for cancer theranostics Forensic Fingerprint Detection Methods

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
6
Pages
1976–1982
Publication date
28 January 2026
Language
EN