(Vinyl tosyloxy)benziodolium Salts: Divergent Construction of Conjugated Diene Derivatives via Sequential Coupling Reactions

Organic Letters 2026

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Authors: Cheng Pan, Hamza Khan, Xiaoting Liu, Limin Wang, Jianwei Han
DOI: 10.1021/acs.orglett.5c05448
Cited by: 4
References: 26

Abstract

Using (vinyl tosyloxy)benziodolium salts, we divergently synthesized a series of conjugated diene derivatives with the Mizoroki–Heck reaction. Subsequent coupling reactions of these dienes provide access to polycyclic aromatic conjugated diene derivatives. Derivatization of ester-substituted conjugated dienes enabled the synthesis of ortho -iodoarylpyranones. Further oxidation of ortho -iodoarylpyranones furnishes cyclic arylidonium salts, which serve as versatile reagents for polycyclic aromatic hydrocarbons.

Fields of Study & Subjects

Catalytic Cross-Coupling Reactions Synthesis and pharmacology of benzodiazepine derivatives Catalytic C–H Functionalization Methods

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
6
Pages
2143–2147
Publication date
2 February 2026
Language
EN