Yellow-Light-Mediated Synthesis of Amidoximes via Radical gem -Diamination of Diazo Compounds
Abstract
N -Nitrosamines serve as bifunctional reagents to install both amino and nitroso groups across unsaturated bonds, yet their use as diamine reagents remains underdeveloped. Herein, we introduce a simple yellow-light-driven reaction that directly forms amidoximes from N -nitrososulfonamides and diazo compounds. The process works by selectively activating the N–NO bond with low-energy light (λ > 590 nm), thereby avoiding side reactions and ensuring high selectivity.
Fields of Study & Subjects
Radical Photochemical Reactions
Synthesis and Catalytic Reactions
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Volume
- 28
- Issue
- 7
- Pages
- 2410–2414
- Publication date
- 4 February 2026
- Language
- EN