Vinylsilanes as Ethylene Surrogates: Rh(I)-Catalyzed Direct Hydroarylation of In Situ Generated Ethylene
Abstract
A modular and practical approach to the Rh(I)-catalyzed hydroarylation of ethylene with arenes bearing a quinoline amide group has been developed. To address the inherent challenges of ethylene hydroarylation, particularly the reliance on high ethylene pressure, this approach employs vinylsilane as a bench-stable, safer surrogate for the in situ generation of ethylene. Comprehensive mechanistic studies support a sequence involving the insertion of vinyl silane, ethylene release, and subsequent hydroarylation, highlighting the efficiency and practicality of this transformation.
Fields of Study & Subjects
Catalytic C–H Functionalization Methods
Catalytic Alkyne Reactions
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Volume
- 28
- Issue
- 23
- Pages
- 7065–7070
- Publication date
- 19 February 2026
- Language
- EN