Cyclicurilarenes: Hybridizing Bambusurils with Macrocyclic Arenes
Abstract
Our cyclicurilarene receptor family has been extended by coupling of 2,4-dimethylglycoluril with bis(bromomethyl)-substituted dimethoxybenzene through nucleophilic substitution, yielding macrocycles with conformational flexibility that can adapt to different-sized substrates, resembling bambusurils. Anti/syn-configurations of the two glycoluril units in "Ding"-shaped cyclicurilarenes induce distinct acetonitrile positions in the solid state, and inward-oriented glycoluril forms intracavity hydrogen bonds with alanine derivative in chloroform. Four- and six-membered cyclicurilarenes featuring alternating dimethoxybenzene and glycoluril units were synthesized.
Fields of Study & Subjects
Synthesis and Properties of Aromatic Compounds
Supramolecular Chemistry and Complexes
Molecular Sensors and Ion Detection
Publication details
- Journal / source
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Volume
- 28
- Issue
- 13
- Pages
- 3982–3986
- Publication date
- 25 March 2026
- Language
- EN