Photoredox/Copper Dual-Catalyzed Four-Component Regioselective 1,2-Arylsulfonylation of Vinylarenes

Organic Letters 2026

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Authors: Yunyi Zhang, Lingyu Shi, Patiman Turgun, Chaoyu Wu, Jian Lv, Yongjia Shi, Daoshan Yang
DOI: 10.1021/acs.orglett.6c00500
Cited by: 5
References: 54

Abstract

Sulfones and their derivatives serve as important structural units in organic chemistry. However, there is currently a lack of simple and feasible synthetic methods for their synthesis. In this wotk, a photoredox/copper dual catalysis that enabled 1,2-arylsulfonylation of vinylarenes to afford 2,2-diarylethyl sulfones has been reported for the first time. The developed protocol features high reaction regioselectivity and good reaction generality, affording a facile approach to 2,2-diarylethyl sulfones.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Radical Photochemical Reactions Catalytic C–H Functionalization Methods

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
11
Pages
3535–3540
Publication date
11 March 2026
Language
EN