Synthesis of Vinyl Sulfoxides and Subsequent Construction of C,S Contiguous Stereocenters Via Thia-Stevens Rearrangement of I III /S VI -Hybrid Ylides

Organic Letters 2026

View at publisher
Authors: Kun Deng, Mei Hu, Zelong Du, Hongbin Zheng, Jie Cai, Jiean Chen, Zhili Wang
DOI: 10.1021/acs.orglett.6c01051
Cited by: 3
References: 55

Abstract

-hybrid ylides into vinyl sulfoxides. Using Oppolzer's camphorsultam as a chiral auxiliary, a one-pot stereoselective [1,2]-thia-Stevens rearrangement/Michael addition cascade was further realized with a broad range of nucleophiles, delivering products bearing contiguous C,S-stereocenters.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Cyclopropane Reaction Mechanisms Synthesis of heterocyclic compounds

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
20
Pages
6184–6189
Publication date
8 May 2026
Language
EN