Switchable C or C–N Insertion into N -Alkyl Enamines for Divergent Synthesis of 3-Aminopyrroles or CF 3 /CN-1,2-Dihydropyrazines

Organic Letters 2026

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Authors: Gui-Ting Song, Suya Liu, Lin Zhu, Ying Cheng, Shi-You Xue, Ruixue Luo, Chuan‐Hua Qu
DOI: 10.1021/acs.orglett.6c01107
Cited by: 2
References: 47

Abstract

or CN groups that are otherwise difficult to install. The protocol streamlines the construction of two distinct nitrogen heterocycles from a common enamine platform, offering a rare example of reactivity-controlled divergent synthesis in C-C and C-N bond formation.

Fields of Study & Subjects

Fluorine in Organic Chemistry Synthesis and Characterization of Pyrroles Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
15
Pages
4987–4992
Publication date
8 April 2026
Language
EN