Low-Energy Light-Driven Excited-State Palladium Catalysis: Cross-Coupling of Pyridine N -Oxides with Unactivated Alkyl Bromides
Abstract
High Resolution Image Download MS PowerPoint Slide Excited-state Pd catalysis has emerged as a new platform for cross-coupling reactions. Nonetheless, such catalysis typically requires high-energy near-ultraviolet (NUV) or blue (380–450 nm) light. In contrast, the use of lower-energy light (>520 nm) in excited-state Pd catalysis remains largely unexplored. Herein, we report a low-energy light-driven excited-state Pd-catalyzed cross-coupling of pyridine N -oxides with unactivated alkyl bromides. Mechanistic studies reveal the formation of a Pd(0)–pyridine N -oxide complex that absorbs low-energy light.
Fields of Study & Subjects
Catalytic Cross-Coupling Reactions
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Volume
- 28
- Issue
- 20
- Pages
- 6208–6213
- Publication date
- 8 May 2026
- Language
- EN