Photoinduced Synthesis of γ-Amino Alcohols via [2,3]-Acyloxy Migration

Organic Letters 2026

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Authors: Tingting Yuan, Xi Zhang, Zhen-Zhen Ruan, Xuan Deng, Bin Cheng, Ya‐Jian Hu, Yu‐Tao He
DOI: 10.1021/acs.orglett.6c01217
Cited by: 3
References: 60

Abstract

An efficient photoinduced strategy for the synthesis of γ -amino alcohols via intramolecular [2,3]-acyloxy migration is described. This transformation enables the direct synthesis of γ -amino alcohols, valuable intermediates in organic synthesis, through N -centered radical addition, intramolecular acyloxy migration, and subsequent nucleophilic attack.

Fields of Study & Subjects

Radical Photochemical Reactions Catalytic C–H Functionalization Methods Oxidative Organic Chemistry Reactions

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
20
Pages
6232–6238
Publication date
8 May 2026
Language
EN