Exploring the Construction of a Fused-Ring Triazolopyrimidine Energetic Molecule

Organic Letters 2026

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Authors: Tianyu Jiang, Yuhong Cao, Youhai Liu, S X Chen, Hai Yan Wang, Xue-hai Ju, Yongxing Tang, Wenquan Zhang
DOI: 10.1021/acs.orglett.6c01244
Cited by: 1
References: 42

Abstract

Achieving the effortless synthesis of energetic molecules remains coveted, which conforms to the application requirements. This study reports the synthesis of a novel triazolopyrimidine energetic molecule ( 2 ) via thermally induced denitrogenation and cyclization of a tetrazole precursor, followed by oxidation to yield 3 . The two products both exhibit excellent thermostability. The work demonstrates the skeleton construction that converts an imino-bridged ring into a fused-ring structure, offering valuable insights for synthesizing fused-ring energetic molecules.

Fields of Study & Subjects

Chemical Reaction Mechanisms Synthesis and Reactivity of Heterocycles Click Chemistry and Applications

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
17
Pages
5586–5591
Publication date
15 April 2026
Language
EN