Csp 3 –H Bond Carbynoid Functionalization by Photoredox Catalysis

Organic Letters 2026

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Authors: Lixing Shen, S S Chen, J S Peng, Ying Xie, J D Li, Huanfeng Jiang, Wei Zeng
DOI: 10.1021/acs.orglett.6c01646
Cited by: 1
References: 34

Abstract

-H carbynoid functionalization of 1,3-dicarbonyl compounds with α-iodionium diazo compounds has been developed to rapidly assemble α,β-diacyl-α,β-unsaturated ketones. This protocol offers a straightforward approach to access β-deuterated-α,β-unsaturated carbonyl molecules via a 1,2-H shift process.

Fields of Study & Subjects

Cyclopropane Reaction Mechanisms Chemical Reactions and Isotopes Catalytic C–H Functionalization Methods

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
21
Pages
6761–6766
Publication date
18 May 2026
Language
EN