Photoinduced Radical Phosphonylation of Alkyl Thianthrenium Salts with P(III) Reagents via Electron Donor–Acceptor Complexes

Organic Letters 2026

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Authors: Kui Hu, Feiyang Rao, Yuanxiang He, Ziyi Zuo, Shu Geng, Runli Gao, Li Pan, Feng Huang, Hongmei Wang
DOI: 10.1021/acs.orglett.6c01858
Cited by: 1
References: 54

Abstract

A photoinduced radical phosphonylation protocol has been developed for the efficient synthesis of alkyl phosphonates. This transformation proceeds through the formation of electron donor–acceptor (EDA) complexes between alkyl thianthrenium salts and P(III) reagents, which can be directly activated by light irradiation without the need for external photocatalysts or additives. The reaction exhibits broad substrate scope, tolerating various functional groups, offering a sustainable approach for C(sp 3 )–P bond formation.

Fields of Study & Subjects

Radical Photochemical Reactions Sulfur-Based Synthesis Techniques Organophosphorus compounds synthesis

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
25
Pages
8006–8011
Publication date
16 June 2026
Language
EN