S -Aminodibenzo[ b ]thiophenium Salts as Precursors for the Photoredox-Catalyzed Generation of Sulfamoyl Radicals

Organic Letters 2026

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Authors: Kamil Hofman, Kathrin J. Horst, Eslam A. Ghaith, Stephanie L. Faber, Jonathan Becker, Georg Manolikakes
DOI: 10.1021/acs.orglett.6c02511
Cited by: 1
References: 51

Abstract

S -Aminodibenzo[ b ]thiophenium salts, accessible from S -methoxydibenzo[ b ]thiophenium tetrafluoroborate and the parent amines, are introduced as alternative precursors for the in situ generation of sulfamoyl radicals. Irradiation of S -aminodibenzo[ b ]thiophenium salts and the solid SO 2 surrogate DABSO with visible light in the presence of the organic photoredox catalyst Eosin Y affords sulfamoyl radicals as versatile reactive intermediates for the synthesis of sulfonamides. The utilization of this approach is demonstrated in the three-component synthesis of β-ketosulfonamides.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Radical Photochemical Reactions Synthesis and Catalytic Reactions

Publication details

Journal / source
Organic Letters
Publisher
American Chemical Society (ACS)
Volume
28
Issue
29
Pages
9366–9370
Publication date
10 July 2026
Language
EN