Skin Substitutes: Ushering in a New Era of Transition from Traditional Dressings to Bioprinted Scaffolds

ACS Applied Bio Materials 2026

View at publisher
Authors: Hongfan Ding, Pianpian Lin, Wensi Wu, Guiwen Zhou, Qiang Fu, Guangdi Li, Jide Jin, Yiming Wang, Fanting Meng, Xiao Yan Xu, Minliang Chen
DOI: 10.1021/acsabm.5c01879
Cited by: 3
References: 330

Abstract

3D bioprinting has revolutionized wound management by addressing the clinical challenges posed by chronic wounds and acute skin defects. While traditional skin substitutes serve critical roles in wound healing, current research focuses on optimizing bioprinting techniques, bioink formulations, and functional biological dressings to enhance tissue regeneration. The field is rapidly advancing through integration with nanotechnology, organoid technology, and microfluidics, while emerging approaches such as AI-assisted, in situ, and 4D bioprinting offer new therapeutic dimensions. This technological evolution necessitates continued innovation to overcome the existing limitations in clinical translation.

Fields of Study & Subjects

3D Printing in Biomedical Research Wound Healing and Treatments Planarian Biology and Electrostimulation

Publication details

Journal / source
ACS Applied Bio Materials
Publisher
American Chemical Society (ACS)
Volume
9
Issue
3
Pages
1234–1264
Publication date
14 January 2026
Language
EN