Phototriggered Self-Adhesive Soybean Protein-Based Hydrogels for Promoting Chronic Wound Healing
Abstract
Soybean protein hydrogel wound dressings were developed using thiol-grafted soy protein isolate and ultraviolet-induced polymerization. Gallic acid-grafted soy protein side chains were incorporated to enhance the adhesion and degradation properties of the hydrogel, resulting in a self-adhesive interpenetrating dual-network hydrogel. Physicochemical characterization and cellular experiments demonstrated that the hydrogel exhibited excellent self-adhesion, degradability, and antioxidant properties, in addition to a good biocompatibility. Furthermore, in a chronic full-thickness wound model in C57 mice, the hydrogel significantly promoted wound healing, highlighting its potential for application as a biomedical wound dressing.
Fields of Study & Subjects
Wound Healing and Treatments
Hydrogels: synthesis
properties
applications
Silk-based biomaterials and applications
Publication details
- Journal / source
- ACS Applied Polymer Materials
- Publisher
- American Chemical Society (ACS)
- Volume
- 8
- Issue
- 10
- Pages
- 7066–7075
- Publication date
- 4 May 2026
- Language
- EN