From Prompt to Drug: Toward Pharmaceutical Superintelligence

Read full text
Authors: Alex Zhavoronkov, David Gennert, Jiye Shi
Cited by: 7
References: 151

Abstract

The convergence of generative artificial intelligence (AI) platforms and automated laboratory systems is ushering in a new era of drug discovery, in which a plain-language prompt can initiate a fully autonomous, end-to-end drug development program. This article explores the recent evolution of AI technologies and presents a "prompt-to-drug" pipeline, where AI not only generates novel hypotheses and designs optimized drug candidates but also orchestrates synthesis, validation, and clinical planning in a closed-loop system. By highlighting key breakthroughs, case studies, and the technological infrastructure required for this paradigm shift, we outline a vision for scalable, efficient, and unbiased drug discovery.

Fields of Study & Subjects

Computational Drug Discovery Methods Machine Learning in Materials Science Scientific Computing and Data Management

Publication details

Journal / source
ACS Central Science
Publisher
American Chemical Society (ACS)
Volume
12
Issue
3
Pages
265–279
Publication date
2 February 2026
Language
EN