In Vitro Effect-Based Analysis of Stormwater Pond Sediments: Linkage to the Organic Contaminant Profile
Abstract
Abstract This study investigated the relationship between biological effects and contamination profiles in sediments from 17 stormwater sedimentation facilities across four Swedish municipalities. Sediment extracts were examined using a battery of in vitro bioassays targeting five modes of action: aryl hydrocarbon (AhR), estrogenic (ER), androgenic (AR), antiandrogenic (AntiAR) receptors, and oxidative stress (Nrf2) activities, along with cytotoxicity. Significant differences in biological activities across cities aligned with patterns in previously characterized profiles of 259 urban-sourced organic substances. Concentrations of bioactive substances correlated positively with biological activities; however, they explained only a limited fraction (typically
Fields of Study & Subjects
Pharmaceutical and Antibiotic Environmental Impacts
Effects and risks of endocrine disrupting chemicals
Toxic Organic Pollutants Impact
Publication details
- Journal / source
- ACS ES&T Water
- Publisher
- American Chemical Society (ACS)
- Volume
- 6
- Issue
- 2
- Pages
- 884–902
- Publication date
- 13 January 2026
- Language
- EN