Novel 6-Aminopurine Derivatives as POLQ Inhibitors for Treating Cancer

ACS Medicinal Chemistry Letters 2026 Open access

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Authors: Ram W. Sabnis
DOI: 10.1021/acsmedchemlett.5c00766
Cited by: 1
References: 3

Abstract

High Resolution Image Download MS PowerPoint Slide Provided herein are novel 6-aminopurine derivatives as POLQ inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds.

Fields of Study & Subjects

Retinoids in leukemia and cellular processes Cancer-related Molecular Pathways Protein Kinase Regulation and GTPase Signaling

Publication details

Journal / source
ACS Medicinal Chemistry Letters
Publisher
American Chemical Society (ACS)
Volume
17
Issue
2
Pages
292–293
Publication date
2 January 2026
Language
EN