Novel Acrylamide Derivatives as Mitochondrial Permeability Transition Pore (mPTP) Inhibitors for Treating Neurodegenerative Diseases

ACS Medicinal Chemistry Letters 2026 Open access

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Authors: Ram W. Sabnis, Anika R. Sabnis
DOI: 10.1021/acsmedchemlett.5c00778
Cited by: 0
References: 6

Abstract

High Resolution Image Download MS PowerPoint Slide Provided herein are novel acrylamide derivatives as mitochondrial permeability transition pore (mPTP) inhibitors, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, and processes for preparing such compounds.

Fields of Study & Subjects

Cancer Research and Treatment Chemotherapy-induced organ toxicity mitigation Sulfur Compounds in Biology

Publication details

Journal / source
ACS Medicinal Chemistry Letters
Volume
17
Issue
2
Pages
298–299
Publication date
6 January 2026
Language
EN