Novel Substituted Pyrazolo-Pyrimidine Compounds as PIKfyve Inhibitors for Treating Neurological Diseases

ACS Medicinal Chemistry Letters 2026 Open access

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Authors: Ram W. Sabnis, Anika R. Sabnis
DOI: 10.1021/acsmedchemlett.6c00012
Cited by: 0
References: 4

Abstract

High Resolution Image Download MS PowerPoint Slide Provided herein are novel substituted pyrazolo-pyrimidine compounds as PIKfyve inhibitors, pharmaceutical compositions, use of such compounds in treating neurological diseases, and processes for preparing such compounds.

Fields of Study & Subjects

PI3K/AKT/mTOR signaling in cancer Synthesis and biological activity Protein Kinase Regulation and GTPase Signaling

Publication details

Journal / source
ACS Medicinal Chemistry Letters
Volume
17
Issue
2
Pages
317–318
Publication date
12 January 2026
Language
EN