Novel Macrocyclic Compounds Targeting STING for Autoimmune Diseases Treatment
Abstract
This patent demonstrates a series of macrocycle-based compounds that antagonize stimulator of interferon genes (STING), a key role in the innate immune response implicated in autoimmune diseases. These compounds, along with their pharmaceutically acceptable salt thereof, are intended for the treatment of autoimmune related diseases driven by STING-mediated pathways.
Fields of Study & Subjects
interferon and immune responses
Cytokine Signaling Pathways and Interactions
Respiratory viral infections research
Publication details
- Journal / source
- ACS Medicinal Chemistry Letters
- Publisher
- American Chemical Society (ACS)
- Volume
- 17
- Issue
- 5
- Pages
- 1018–1021
- Publication date
- 22 April 2026
- Language
- EN