Self-Cascading Copper-Based Nanoassemblies Trigger Bacterial Cuproptosis-Like Death and Promote Wound Healing for Diabetic Drug-Resistant Bacterial Infections

ACS Nano 2026

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Authors: Tianji Feng, Wenjie Fan, Yin Zhang, Yuexin Yang, Xiaohui Song, Yueyang Zhong, Qiao Jin, Lidan Hu, Ke Yao, Haijie Han
DOI: 10.1021/acsnano.5c21619
Cited by: 5
References: 57

Abstract

facilitates tissue regeneration. MRSA-infected diabetic foot ulcers and diabetic MRSA keratitis models validated DC/Cu's multifunctional efficacy in bacterial eradication, inflammatory mitigation, and tissue regeneration. Collectively, these multifunctional nanoassemblies demonstrate a promising and effective approach for precision therapeutic intervention against MDR pathogen-aggravated diabetic complications.

Fields of Study & Subjects

Graphene and Nanomaterials Applications Ocular Infections and Treatments Wound Healing and Treatments

Publication details

Journal / source
ACS Nano
Publisher
American Chemical Society (ACS)
Volume
20
Issue
18
Pages
13598–13615
Publication date
29 April 2026
Language
EN