From the Gut to the Brain: Modeling Intestinal Absorption and Assessing Blood–Brain-Barrier Permeability of Small-Molecule Drugs by IAM Chromatography

ACS Omega 2026 Open access

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Authors: Stefan Simić, Predrag Kalaba, Judith Wackerlig, Thierry Langer
DOI: 10.1021/acsomega.6c00701
Cited by: 1
References: 72

Abstract

molecular descriptors yields a predictive model for intestinal absorption, offering a powerful tool for early permeability profiling in drug discovery.

Fields of Study & Subjects

Protein Interaction Studies and Fluorescence Analysis Barrier Structure and Function Studies Drug Transport and Resistance Mechanisms

Publication details

Journal / source
ACS Omega
Publisher
American Chemical Society (ACS)
Volume
11
Issue
26
Pages
38581–38593
Publication date
25 June 2026
Language
EN