Modeling and Optimization of α-Amylase Immobilization on Chitosan-Based Supports: A Comparison of Response Surface Methodology and Machine Learning Approaches
Abstract
Amy@GA-CS retained approximately 50% of its initial activity after ten consecutive reuses, demonstrating strong operational stability. Overall, this study highlights the complementary strengths of the RSM and ML in designing robust immobilized enzymes and provides a solid foundation for the development of reusable biocatalysts.
Fields of Study & Subjects
Enzyme Production and Characterization
Enzyme Catalysis and Immobilization
Advanced Drug Delivery Systems
Publication details
- Journal / source
- ACS Omega
- Publisher
- American Chemical Society (ACS)
- Volume
- 11
- Issue
- 17
- Pages
- 25861–25873
- Publication date
- 7 April 2026
- Language
- EN