Engineering and Application of a Thermostable MHETase for PET Depolymerization

ACS Sustainable Chemistry & Engineering 2026 Open access

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Authors: Natasha P. Murphy, Japheth E. Gado, Tabea Neumann, Pablo Pérez-García, Evan Komp, Luisana Avilán, Irimpan I. Mathews, Elizabeth L. Bell, Brenna Norton‐Baker, Matilda Clark, Rebecca R. Garcia, Hannah M. Alt
+6 more Ritimukta Sarangi, Andrew R. Pickford, Wolfgang R. Streit, J.E. McGeehan, Nicholas P. Gauthier, Gregg T. Beckham
DOI: 10.1021/acssuschemeng.6c01404
Cited by: 1
References: 78

Abstract

, which reduced MHET accumulation in bioreactor experiments with postconsumer PET waste. Overall, this study expands the known MHET-hydrolyzing protein scaffolds available for enzymatic PET recycling.

Fields of Study & Subjects

Peptidase Inhibition and Analysis Enzyme Structure and Function Enzyme Catalysis and Immobilization

Publication details

Journal / source
ACS Sustainable Chemistry & Engineering
Publisher
American Chemical Society (ACS)
Volume
14
Issue
24
Pages
10981–10995
Publication date
8 June 2026
Language
EN