De Novo High-Titer Biosynthesis of (−)-α-Bisabolol in Engineered Candida tropicalis via Green Metabolic Engineered Strategies

ACS Synthetic Biology 2026

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Authors: Haiquan Yang, Lingling Chen, Wei Shen, Yuanyuan Xia, Li Zhou, Xianzhong Chen
DOI: 10.1021/acssynbio.5c00625
Cited by: 5
References: 38

Abstract

. This study demonstrated a green, scalable biosynthesis platform for (-)-α-bisabolol, reducing reliance on petrochemical or plant-extraction routes, and provided a sustainable blueprint for terpenoid production in nonconventional yeasts.

Fields of Study & Subjects

Plant biochemistry and biosynthesis Microbial Metabolic Engineering and Bioproduction Microbial Natural Products and Biosynthesis

Publication details

Journal / source
ACS Synthetic Biology
Publisher
American Chemical Society (ACS)
Volume
15
Issue
2
Pages
522–533
Publication date
21 January 2026
Language
EN