Synthetic Intrinsically Disordered Proteins Enable Soluble Expression of Disulfide-Rich Therapeutics in E. coli

ACS Synthetic Biology 2026

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Authors: Yulia Shmidov, Parul Sirohi, Jonathan C. Su, Joy (Shijia). Tong, Rohit Suresh, Joshua J. Milligan, Daniel M. Shapiro, Ashutosh Chilkoti

DOI: 10.1021/acssynbio.6c00115

Cited by: 1

References: 39

Abstract

We previously reported the de novo design of three small (

Protein purification and stability Click Chemistry and Applications Biochemical and Structural Characterization

References 39