Cobalt-Catalyzed Carbonylative Conversion of Unactivated Alkyl Chlorides

Journal of the American Chemical Society 2026 Open access

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Authors: Chunqiang Xu, Yuanrui Wang, Guang Zeng, Xiao‐Feng Wu
DOI: 10.1021/jacs.6c03507
Cited by: 4
References: 29

Abstract

2-type C-Cl activation. This system accommodates sterically hindered nucleophiles and proceeds through a well-supported radical-involved organocobalt catalytic cycle, providing a general platform for carbonylation of challenging alkyl chlorides.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions Radical Photochemical Reactions

Publication details

Journal / source
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Volume
148
Issue
13
Pages
14652–14661
Publication date
30 March 2026
Language
EN