Machine-Learning-Guided Discovery of Cytochrome P450 Enzymes for Bioproduction of Jolkinolides and Other Labdane-Related Diterpenoids

Journal of the American Chemical Society 2026

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Authors: Kaizhou Lu, Rui Zhang, Ke Gao, Ni Li, Zihan Cai, Jianxun Zhu, Jiachen Zi
DOI: 10.1021/jacs.6c05010
Cited by: 1
References: 42

Abstract

, respectively. These findings provide a high-performance approach for identifying CYPs from plant genomes and enrich the enzymatic catalysts for bioproduction of jolkinolides and other valuable LRDs.

Fields of Study & Subjects

Plant biochemistry and biosynthesis Microbial Natural Products and Biosynthesis Biological Activity of Diterpenoids and Biflavonoids

Publication details

Journal / source
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Volume
148
Issue
18
Pages
19369–19380
Publication date
29 April 2026
Language
EN