Long-term sustainability and safety of a delivery-based early-onset sepsis evaluation strategy for very low birth weight infants

Journal of Perinatology 2026 Open access

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Authors: Molly F. May, Alvaro Zevallos Barboza, Samuel J. Garber, Karen Marie Puopolo, Sagori Mukhopadhyay, Dustin Daniel Flannery
DOI: 10.1038/s41372-026-02607-y
Cited by: 0
References: 4

Abstract

Empiric antibiotics are given to about 80% of very low birth weight (VLBW) infants in the United States for concern of early-onset sepsis (EOS) [ 1 ]. We previously reported that implementing a delivery-based risk-stratification guideline for EOS evaluation among preterm infants in1 our level III neonatal intensive care unit (NICU), consistent with American Academy of Pediatrics (AAP) recommendations, was associated with reduced early antibiotic use without safety concerns [ 2 , 3 ].

Fields of Study & Subjects

Neonatal and Maternal Infections Infant Development and Preterm Care Preterm Birth and Chorioamnionitis

Publication details

Journal / source
Journal of Perinatology
Volume
46
Issue
5
Pages
865–867
Publication date
13 March 2026
Language
EN