Neonatal acute kidney injury: a survey of practices in Canadian neonatal intensive care units

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Authors: Abbeir Hussein, Linda Ding, Kyong‐Soon Lee, Cherry Mammen, Marc Beltempo, Prakesh S. Shah, Po‐Yin Cheung, Catherine Morgan, Joseph Yuk Ting, on behalf of the Canadian Neonatal Network Investigators, Marc Beltempo, Prakesh S. Shah
+39 more Thevanisha Pillay, Jonathan Wong, Miroslav Stavel, Rebecca Sherlock, Ayman Abou Mehrem, Jennifer Toye, Joseph Yuk Ting, Carlos Enrique Sabbagh Fajardo, Andrei Harabor, Lannae Strueby, MM Seshia, Deepak Louis, Chelsea Ruth, Ann Yi, Amit Mukerji, Orlando Da Silva, Sajit Augustine, Kyong‐Soon Lee, Eugene Ng, Brigitte Lemyre, Brigitte Lemyre, Faiza Khurshid, Victoria Bizgu, Keith James Barrington, Anie Lapointe, Guillaume Ethier, Christine Drolet, Martine Claveau, Marie St‐Hilaire, Valérie Bertelle, Edith Masse, Caio Barbosa de Oliveira, Hala Makary, Gabriela de Carvalho Nunes, Wissam Alburaki, Jo-Anna Hudson, Jehier Afifi, Andrzej Kajetanowicz, Bruno Piedboeuf
Cited by: 1
References: 24

Abstract

OBJECTIVE: To assess current practices in the diagnosis, monitoring, and follow-up of neonatal AKI across Canadian tertiary neonatal units. STUDY DESIGN: A seven-item electronic survey was distributed to members of the Canadian Neonatal Network between December 2023 and January 2024. RESULTS: Of the 32 units contacted, 26 (81.3%) responded. On-site nephrology consultation was available at 15/26 sites (57.7%). Only 5 sites (19.2%) actively tracked AKI incidence in infants born < 33 weeks' gestation. Wide variation was observed in AKI definitions, monitoring practices, and follow-up protocols. Serum creatinine was measured prior to initiating non-steroidal anti-inflammatory drugs at 15 sites (57.7%), and 11 sites (42.3%) monitored creatinine when urine output fell below 0.5 mL/kg/hour. CONCLUSIONS: Substantial variability exists in the identification and monitoring of neonatal AKI among Canadian NICUs. Standardized diagnostic criteria and follow-up strategies are needed to improve early detection and optimize long-term renal outcomes.

Fields of Study & Subjects

Acute Kidney Injury Research Pregnancy and Medication Impact Nephrotoxicity and Medicinal Plants

Publication details

Journal / source
Journal of Perinatology
Publisher
Springer Science and Business Media LLC
Publication date
30 March 2026
Language
EN