Paracetamol as analgesic and risk of bronchopulmonary dysplasia in extremely preterm infants: a secondary analysis of the BeNeDuctus trial

Pediatric Research 2026 Open access

Read full text
Authors: Lindy W. Hoornenborg, Laura W. Hafner, Clyde J. Wright, Willem P. de Boode, Eduardo Villamor, Tim Hundscheid, on behalf of the BeNeDuctus trial study group
DOI: 10.1038/s41390-026-05352-2
Cited by: 1
References: 51

Abstract

BACKGROUND: Paracetamol is increasingly used as analgesic and to treat patent ductus arteriosus (PDA) in preterm infants, though preclinical data suggest it may potentially harm the developing lung. The BeNeDuctus trial compared expectant PDA management versus ibuprofen in infants with gestational age

Fields of Study & Subjects

Neonatal Respiratory Health Research Cardiovascular Conditions and Treatments Pediatric Pain Management Techniques

Publication details

Journal / source
Pediatric Research
Publisher
Springer Science and Business Media LLC
Publication date
31 July 2026
Language
EN