What does not kill you makes you Weaker!
Abstract
Tumor cell evasion from regulated cell death is a hallmark of cancer [1]. Davern et al. now identify resistance to mitochondrial apoptosis to represent the common mechanism by which persister cells that survived either immunotherapy- or irradiation-treatment rely on to proliferate. Therefore, they discovered the persister cells´ Achilles heel for future treatments with BH3-mimetics [2].
Fields of Study & Subjects
Cell death mechanisms and regulation
Mitochondrial Function and Pathology
Cancer
Hypoxia
and Metabolism
Publication details
- Journal / source
- Cell Death and Differentiation
- Volume
- 33
- Issue
- 7
- Pages
- 1310–1311
- Publication date
- 5 January 2026
- Language
- EN