Targeting the USP7-PRMT6 epigenetic axis overcomes chemoresistance in breast cancer by coordinating H3R2me2a deposition and RNF168 methylation for DNA repair and ferroptosis blockade

Cell Death and Differentiation 2026 Open access

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Authors: Tianshu Yang, Hong Wen, Jing Zhang, Yiyang Pan, Yang Feng, Xuan Wu, Jun Zhao, Ke Peng, Lijie Yang, Jie Mei, Yujiao Cai, Yan Wang

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Weidong Xiao

DOI: 10.1038/s41418-026-01672-2

Cited by: 2

References: 46

Fields of Study & Subjects

Cancer-related gene regulation Ferroptosis and cancer prognosis Protein Degradation and Inhibitors

References 46