Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae

Nature Communications 2026 Open access

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Authors: Yi Yang, Willem van Schaik, Alan McNally, Zhiyong Zong
DOI: 10.1038/s41467-026-69690-9
Cited by: 2
References: 24

Abstract

Klebsiella pneumoniae intestinal colonization contributes to infectious and non-infectious diseases. Recent studies have uncovered the complex interplay between the gut microbiota and K. pneumoniae colonization, highlighting its role in disease development and progression and illustrating the potential of microbiome-based therapies. Yang et al. summarize that Klebsiella pneumoniae affects infectious and non-infectious disease via gut colonization; commensals provide colonization resistance, but K. pneumoniae adapts via multiple mechanisms.

Fields of Study & Subjects

Gut microbiota and health Antibiotic Resistance in Bacteria Clostridium difficile and Clostridium perfringens research

Publication details

Journal / source
Nature Communications
Publisher
Springer Science and Business Media LLC
Volume
17
Issue
1
Pages
1761–1761
Publication date
16 February 2026
Language
EN