Hydrogen transfer-triggered C(sp3)−C(sp3) cleavage of 1,3-diols for mono-N-methylation of primary amines

Nature Communications 2026 Open access

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Authors: Yang Long, Jun Liu, Lei Chen, Jun Dong, Xinhao Fan, Lang Qu, Zhishan Su, Y.-Q. Zheng
DOI: 10.1038/s41467-026-71217-1
Cited by: 1
References: 64

Abstract

Here, the authors establish 1,3-propanediol, a low-cost biomass-derived bulk chemical, as an efficient, green, and sustainable C1 source for the mono-N-methylation of primary amines, via chelation-free C(sp3)−C(sp3) bond cleavage.

Fields of Study & Subjects

Asymmetric Hydrogenation and Catalysis Catalysis for Biomass Conversion Catalytic C–H Functionalization Methods

Publication details

Journal / source
Nature Communications
Publisher
Springer Science and Business Media LLC
Volume
17
Issue
1
Publication date
28 March 2026
Language
EN