Testing the redox theory of aging under parasitism
Abstract
The redox theory of aging proposes that an oxidative imbalance, possibly amplified by infection, drives senescence. We experimentally evolved mosquitoes under early or late reproduction with or without parasite exposure, and quantified longevity, fecundity, and redox markers. Although selection generated the expected life-history divergence, there was only a poor, non-linear association between a redox gradient and longevity. Thus, oxidative stress contributed to, but did not determine, the evolution of aging.
Fields of Study & Subjects
Genetics
Aging
and Longevity in Model Organisms
Animal Behavior and Reproduction
Evolution and Genetic Dynamics
Publication details
- Journal / source
- npj Aging
- Volume
- 12
- Issue
- 1
- Publication date
- 12 March 2026
- Language
- EN