Microbial landscapes in dairy cow diseases: from localized dysbiosis to inter-organ axes

npj Biofilms and Microbiomes 2026 Open access

Read full text
Authors: Pei Zhong, Ao Ren, Junwei Cui, Cheng Guo, Yanmei Zhang, Qiyu Diao, Xianjun Liu, Naifeng Zhang, Yan Tu, Yanliang Bi
DOI: 10.1038/s41522-026-00988-8
Cited by: 1
References: 223

Abstract

Dairy cow health involves host-microbiome interactions. This review characterized microbial landscapes across anatomical sites in dairy cows-including the gastrointestinal tract, respiratory system, reproductive tract, mammary gland, and skin-and examines their associations with diseases. We elucidated how site-specific dysbiosis drives systemic conditions such as mastitis and ketosis through inter-organ axes. Finally, we evaluated emerging microbiome-based modulation strategies and their application prospects in dairy farming.

Fields of Study & Subjects

Milk Quality and Mastitis in Dairy Cows Reproductive Physiology in Livestock Effects of Environmental Stressors on Livestock

Publication details

Journal / source
npj Biofilms and Microbiomes
Publisher
Springer Science and Business Media LLC
Volume
12
Issue
1
Publication date
17 April 2026
Language
EN