Clinical utility of evoked potentials for programming subthalamic deep brain stimulation in Parkinsons disease

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Authors: Blake Hale, Anna Latorre, Lorenzo Rocchi, John C. Rothwell, Patricia Limousin
Cited by: 3
References: 184

Abstract

Optimal subthalamic nucleus deep-brain stimulation (STN-DBS) for Parkinson's disease reduces motor symptoms without stimulating adjacent structures and causing side-effects. Fine-tuning STN-DBS using clinical evaluation is time-consuming and often requires multiple follow-ups. Electrophysiological recordings may enhance STN-DBS device programming for clinicians by providing objective evidence of neural pathway activation. This literature review critically evaluates evoked potentials as biomarkers of optimal STN-DBS and assesses potential integration into the device programming toolkit.

Fields of Study & Subjects

Neurological disorders and treatments Neuroscience and Neural Engineering EEG and Brain-Computer Interfaces

Publication details

Journal / source
npj Parkinson s Disease
Publisher
Springer Science and Business Media LLC
Volume
12
Issue
1
Publication date
23 January 2026
Language
EN