Seeing through collagen: integrative pro-regenerative corneal implants for clearer future
Abstract
Collagen-based artificial corneas are a promising regenerative alternative to scarce donor tissue. However, their clinical success is limited by mechanical weakness, enzymatic degradation, and poor bio-integration. This review provides a comprehensive analysis of the current state and the future strategies to optimize collagen for making pro-regenerative corneal implants, enhancing the performance, functionality, and clinical viability of the collagen-based artificial cornea as a substitute for donor tissue.
Fields of Study & Subjects
Corneal Surgery and Treatments
Collagen: Extraction and Characterization
Corneal surgery and disorders
Publication details
- Journal / source
- npj Regenerative Medicine
- Publisher
- Springer Science and Business Media LLC
- Volume
- 11
- Issue
- 1
- Publication date
- 14 March 2026
- Language
- EN