β-casomorphin-7: a review of occurrence, identification, techno-functionality, and effects on human health

npj Science of Food 2026 Open access

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Authors: Abdelmoneim H. Ali, Mayssa Hachem, Zain Najjar, Shao‐Quan Liu, Gafar Babatunde Bamigbade, Mutamed Ayyash
DOI: 10.1038/s41538-026-00762-2
Cited by: 3
References: 150

Abstract

β-casomorphin-7 (βCM-7) is a bioactive peptide released after the digestion of β-casein A1 variant, mostly found in European cow breeds' milk. This review explores the occurrence, characteristics, identification, techno-functionality, and the potential health effects of βCM-7. It displays opioid-like properties because of its affinity for μ-opioid receptors, affecting both food texture and biological functions. βCM-7 has potential advantages on immune and gastrointestinal health; however, concerns persist regarding its adverse effects.

Fields of Study & Subjects

Protein Hydrolysis and Bioactive Peptides Food Allergy and Anaphylaxis Research Milk Quality and Mastitis in Dairy Cows

Publication details

Journal / source
npj Science of Food
Publisher
Springer Science and Business Media LLC
Volume
10
Issue
1
Publication date
21 February 2026
Language
EN